Codeine and promethazine is a combination medicine applied to treat cold or allergy signs or symptoms for instance runny nose, sneezing, and cough.

To reduced your threat, your health practitioner ought to have you go ahead and take smallest dose that actually works, and consider it for that shortest doable time. See also How to Use section To find out more about habit.

Reevaluate clients with unresponsive cough in 5 days or sooner for probable underlying pathology, for instance foreign system or reduce respiratory tract condition.

Will not improve your dose or use this product or service extra normally or for for a longer time than prescribed. Your ailment will not likely enhance any speedier, as well as your possibility of Negative effects will increase.

Situations OF USE: The knowledge in this databases is meant to health supplement, not substitute for, the know-how and judgment of Health care industry experts. The knowledge just isn't meant to go over all feasible uses, Instructions, precautions, drug interactions or adverse outcomes, nor need to it be construed to indicate that usage of a specific drug is safe, ideal or successful for you or everyone else.

No proof of tumorigenicity was noticed in male and woman mice at codeine dietary doses nearly 400 mg/kg/day (about such as forty four times the MRHD on a mg/m 2 basis). Codeine was not mutagenic inside the in vitro bacterial reverse mutation assay or clastogenic while in the in vitro Chinese hamster ovary (CHO) mobile chromosomal aberration assay. Fertility scientific tests with codeine haven't been done.

It's not a whole listing of achievable Unwanted side effects. For those who recognize other Unwanted side effects not outlined above, Get hold of your medical doctor or pharmacist.

Considering the fact that Promethazine VC with Codeine is made use of when wanted, you may not be on a dosing program. Skip any skipped dose if It is Nearly time for your personal up coming dose. Tend not to use two doses at 1 time.

3) ], which could improve or read more extend equally the therapeutic outcomes and adverse reactions, and could induce severe respiratory depression. Steer clear of the use of Promethazine with Codeine Oral Remedy in sufferers who're using CYP3A4 inducers. If concomitant use of a CYP3A4 inducer is critical, follow the affected person for lessened efficacy.

The concomitant utilization of Promethazine with Codeine Oral Alternative with all cytochrome P450 2D6 inhibitors (e.g., amiodarone, quinidine) could bring about an increase in codeine plasma concentrations plus a minimize in active metabolite morphine plasma focus which could bring about an analgesic efficacy reduction or signs of opioid withdrawal.

This medication can dry up and thicken mucus as part of your lungs, rendering it more difficult to breathe and distinct your lungs. To aid avert this influence, consume an abundance of fluids Except otherwise directed by your physician.

There isn't any normal settlement about particular pharmacological treatment method regimens for uncomplicated NMS.

Lifestyle-threatening respiratory challenges (respiratory depression). PROMETHAZINE WITH CODEINE ORAL SOLUTION might cause respiration problems (respiratory despair) that will happen Anytime throughout procedure and may result in death. Your chance of breathing troubles is greatest any time you very first get started having PROMETHAZINE WITH CODEINE ORAL Remedy, are having other medicines that could cause respiratory difficulties, have sure lung difficulties, are aged or have particular other health conditions.

Codeine Codeine is an opioid agonist comparatively selective with the mu-opioid receptor, but with a Considerably weaker affinity than morphine. The analgesic and antitussive properties of codeine are already speculated to originate from its conversion to morphine.